About Safety

Juvéderm™ injectable gel is a dermal filler made from hyaluronic acid—a naturally occurring substance in your skin. Juvéderm™ is the first FDA-approved hyaluronic acid dermal filler that has demonstrated its safety and effectiveness in persons of color.

Before you decide on treatment with Juvéderm™ injectable gel, you'll want to find an experienced healthcare professional—someone who is familiar with the injection process. You can use our simple tool to find an experienced doctor near you.

Talking to your healthcare professional about treatment with Juvéderm™

If you're considering treatment with Juvéderm™ injectable gel, your healthcare professional should ask about your medical history to determine if you are an appropriate candidate for treatment. Juvéderm™ injectable gel should not be used in patients who have:

  • Severe allergies marked by a history of anaphylaxis or presence of multiple
    severe allergies
     
  • A history of allergies to gram-positive bacterial proteins

Your healthcare professional should also warn you that the safety and effectiveness of Juvéderm™ injectable gel for the treatment of areas other than facial wrinkles and folds (such as lips) have not been established in controlled clinical studies.

In addition, you and your healthcare professional should discuss the following important treatment considerations in order to help avoid unsatisfactory results and complications:

  • Patients who are using substances that can prolong bleeding, such as aspirin or ibuprofen, as with any injection, may experience increased bruising or bleeding at the injection site. You should inform your healthcare professional before treatment if you are using these types of substances.
     
  • If laser treatment, chemical peeling, or any other procedure based on active dermal response is considered after treatment with Juvéderm™ injectable gel, there is a possible risk of an inflammatory reaction at the treatment site.
     
  • Juvéderm™ injectable gel should be used with caution in patients on immunosuppressive therapy, or therapy used to decrease the body's immune response, as there may be an increased risk of infection.
     
  • The safety of Juvéderm™ injectable gel for use during pregnancy, in breastfeeding females, or in patients under 18 years has not been established.
     
  • The safety of Juvéderm™ in patients with a history of excessive scarring (eg, hypertrophic scarring and keloid formations) and pigmentation disorders has not been studied.

Other treatment options to consider

Other treatments for dermal soft tissue augmentation include bovine-based collagen and other hyaluronic acid-based dermal fillers. Aside from these treatments, additional options for the correction of lines and wrinkles do exist, including facial creams, BOTOX® Cosmetic (botulinum toxin type A), chemical peels, and laser skin surface treatments, and may be discussed with your healthcare professional.

You may also download these helpful materials:

Juvéderm™ Ultra Patient Safety Information

Juvéderm™ Ultra Plus Patient Safety Information

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Important JUVÉDERM™ Treatment Considerations

Juvéderm™ Ultra and Juvéderm™ Ultra Plus are indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Side effects were usually mild to moderate lasting 7 days or less and included temporary injection site reactions like redness, pain, firmness, swelling and bumps. For more information, please click on the “About Safety” link, or call the Allergan Product Support line at 1-877-345-5372.

BOTOX® Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18-65.

Important Safety Information about BOTOX® Cosmetic

Serious heart problems and serious allergic reactions have been reported rarely. If you think you're having an allergic reaction or other unusual symptoms, such as difficulty swallowing, speaking or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis or Lambert-Eaton syndrome may be at increased risk of serious side effects.

Click here for full BOTOX® Cosmetic prescribing information