Administering JUVÉDERM™ Injectable Gel

With its patented HYLACROSS™ gel technology, Juvéderm™ injectable gel is a smooth and malleable product, allowing for ease of administration and moldability so you can deliver an optimal look for your patients. Available in two different formulations, Juvéderm™ also gives you the ability to tailor treatment to your patients' facial aesthetics needs.

Patient satisfaction: Helping to ensure a positive treatment experience

Prior to wrinkle treatment with Juvéderm™ injectable gel, the patient's complete medical history should be reviewed, and the patient should be informed of the details of the treatment process, benefits, results, and potential side effects. In order to set expectations, the patient should also be advised that supplemental “touch up” treatments may be required to achieve and maintain optimal results. Some physicians recommend that the patient should also be advised to discontinue the use of any medications that may prolong bleeding, including aspirin and non-steroidal anti-inflammatories (NSAIDs), at least 1 week prior to treatment with Juvéderm™ in order to reduce the risk of bruising or bleeding at the injection site.

During the consultation visit, the patient's soft tissue deficiencies should be characterized with regard to etiology, distensibility, stress at the site, and depth of lesion. The patient should be advised that, depending on his or her skin type, optimal results are achieved when the defect is readily distensible and correction can be visualized by manual manipulation (stretching) of the skin. It is often helpful to take pre-treatment photographs for comparison with post-treatment results.

Injection Instructions

Product Supply: The Juvéderm™ Ultra and Juvéderm™ Ultra Plus formulations are supplied in individual treatment syringes with 30- or 27-gauge needles for single patient use and ready for injection.

Anesthetic: While anesthesia is not required with Juvéderm™ injectable gel, a topical or injectable anesthesia may be used to manage pain during and after injection.

Injection Technique: The angle and orientation of the bevel, the depth of injection, and the quantity administered may vary. A linear-threading technique, serial puncture injections, or a combination of the two have been used to achieve optimal results. To avoid visible lumps and/or discoloration, avoid injecting Juvéderm™ too superficially.

To administer the gel, apply even pressure on the plunger rod while slowly pulling the needle backwards. The wrinkle should be lifted and eliminated by the end of the injection. To prevent material from leaking or being injected too superficially, be sure to stop the injection just before pulling the needle out of the skin.

Injection Volume: Whether treating with Juvéderm™ Ultra or Juvéderm™ Ultra Plus, the typical volume to achieve optimal correction is 1.6 mL per treatment site. Correct only to 100% of the volume desired. It is important to avoid overcorrection.

Tissue Massage: If immediate blanching occurs, stop the injection and massage the area until it returns to a normal color. The area should also be gently massaged once the injection is completed to help it conform to the contour of the surrounding tissues. If overcorrection occurs, massage the area between your fingers or against an underlying superficial bone to obtain optimal results.

Post Treatment: Patients may have mild to moderate injection site reactions that will typically resolve within a few days. If the patient experiences swelling immediately after the injection, briefly apply an ice pack to the treatment area. In addition, because degree of correction can be difficult to judge in patients with localized swelling, stop the injection if swelling occurs and invite the patient back for a touch-up session in 1 to 2 weeks.

Patient Instructions: The patient should be instructed to avoid strenuous exercise, excessive sun or heat exposure, and alcoholic beverages for 24 hours after treatment in order to minimize the risk of temporary redness, swelling, and/or itching at the injection sites. Advise the patient to call immediately with any problems possibly related to treatment. To report an adverse reaction, phone Allergan Product Support at 877-345-5372.

For complete physician and patient instructions, download the Directions for Use:

Juvéderm™ Ultra DFU

Juvéderm™ Ultra Plus DFU

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Important JUVÉDERM™ Treatment Considerations

Juvéderm™ Ultra and Juvéderm™ Ultra Plus are indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Side effects were usually mild to moderate lasting 7 days or less and included temporary injection site reactions like redness, pain, firmness, swelling and bumps. For more information, please click on the “About Safety” link, or call the Allergan Product Support line at 1-877-345-5372.

BOTOX® Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18-65.

Important Safety Information about BOTOX® Cosmetic

Serious heart problems and serious allergic reactions have been reported rarely. If you think you're having an allergic reaction or other unusual symptoms, such as difficulty swallowing, speaking or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis or Lambert-Eaton syndrome may be at increased risk of serious side effects.

Click here for full BOTOX® Cosmetic prescribing information